Basic Information

IDDRAMP01212
SequenceSIITMTREAKLPQLWKQIACRLYNTC
Length26
NamePleurain-A3 (Pleurain A3; Frogs, amphibians, animals)
SourceRana pleuraden (Yunnan pond frog)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal
Pathogen[Swiss_Prot Entry A8B5P7]has activity against Gram-positive and -negative bacteria, and fungi
Hemolytic Activity[Ref:17764786]Little hemolytic activity on red blood cells even with peptide concentration up to 200 μg/ml
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot A8B5P7
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID17764786

Physicochemical Properties

Residues26
SequenceSIITMTREAKLPQLWKQIACRLYNTC
Molecular Weight3081.677
Grand Average of Hydropathy-0.081
Isoelectric Point9.383
Charge at pH 7.42.198
Secondary StructureHelix: 0.308, Turn: 0.115, Sheet: 0.269
Instability Index51.892
Aromaticity0.077

Similar Structure Search

Candidates based on structure

Address: No.2699 Qianjin Street, Changchun City, China. Zip Code: 130012. 苏ICP备2021057230号-1.