Basic Information

IDDRAMP03038
SequenceLNLKGLIKKVASLLN
Length15
NameEumenitin-R (Insects, animals)
SourceEumenes rubrofemoratus (Solitary wasp)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal
Pathogen[Ref.21549739]Gram-positive bacteria: Staphylococcus aureus ATCC 25923 (MIC=60 µM), Staphylococcus epidermidis (clinical sample) (MIC=30 µM), Micrococcus luteus ATCC 10240 (MIC=15 µM), Streptococcus pyogenes (clinical sample) (MIC=15 µM), Bacillus subtilis ATCC 6633 (MIC=7.5 µM);##Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=30 µM), Proteus mirabilis (clinical sample) (MIC=60 µM), Pseudomonas aeruginosa ATCC 27853 (MIC=30 µM), Stenotrophomonas maltophilia ATCC 13637 (MIC=15 µM);##Fungi: Candida albicans ATCC 90112 (MIC<7.5 µM).
Hemolytic Activity[Ref.21549739]EC50=530.3 μM against mice erythrocytes
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot P0CJ36
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID21549739

Physicochemical Properties

Residues15
SequenceLNLKGLIKKVASLLN
Molecular Weight1624.021
Grand Average of Hydropathy0.64
Isoelectric Point10.302
Charge at pH 7.42.55
Secondary StructureHelix: 0.467, Turn: 0.267, Sheet: 0.400
Instability Index-13.307
Aromaticity0

Similar Structure Search

Candidates based on structure

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