Basic Information

IDDRAMP03042
SequenceINLLKIAKGIIKSL
Length14
NameEumenine mastoparan-AF (EMP-AF; Af-113; Insects, animals)
SourceAnterhynchium flavomarginatum micado (Solitary wasp)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
Pathogen[Ref.15317499]Gram-positive bacteria: Staphylococcus aureus ATCC 6538 (MIC=5 µg/ml), S. saprophyticus CS (MIC=5 µg/ml), S. epidermidis CS (MIC=5 µg/ml), Bacillus subtilis CCT 2471 (MIC=40 µg/ml);##Gram-negative bacteria: Escherichia coli CCT 1371 (MIC=20 µg/ml), Escherichia coli ATCC 25922 (MIC=50 µg/ml), Pseudomonas aeruginosa ATCC 15442 (MIC=20 µg/ml).
Hemolytic Activity[Ref.10775751]100% hemolytic activity against human erythrocytes at 10^-4 M
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot P0C022
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID15317499, 11006592, 10775751

Physicochemical Properties

Residues14
SequenceINLLKIAKGIIKSL
Molecular Weight1523.945
Grand Average of Hydropathy1.057
Isoelectric Point10.302
Charge at pH 7.42.55
Secondary StructureHelix: 0.500, Turn: 0.214, Sheet: 0.286
Instability Index-21.036
Aromaticity0

Similar Structure Search

Candidates based on structure

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