Basic Information
| ID | DRAMP03828 |
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| Sequence | KNLRRITRKIIHIIKKYG |
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| Length | 18 |
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| Name | Novispirin T-7 (mutation of Ovispirin-1) |
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| Source | Synthetic construct |
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| Activity | Antibacterial, Cytotoxic, Anti-Gram+, Anti-Gram-, Antimicrobial |
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| Pathogen | [Ref.11932493]Gram-negative bacteria: Pseudomonas aeruginosa 9 strains (MIC=0.26-27.8 µg/ml), Stenotrophomonas maltophilia 5 strains (MIC=0.32-1.75 µg/ml);##Gram-positive bacteria: Listeria monocytogenes EGD (MIC=2.4±1.5 [n=3] µg/ml), Staphylococcus aureus 930918 (MIC=3.3±1.5 [n=3] µg/ml). |
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| Hemolytic Activity | [Ref.11932493]3% hemolytic at 40 µg/mL, 10% hemolytic activity at 80 µg/mL against human red blood cells |
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| Cytotoxicity | Not included yet |
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| N-terminal Modification | Not included yet |
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| C-terminal Modification | Not included yet |
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| Linear/Cyclic/Branched | Not included yet |
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| Uniprot |
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| PDB |
1HU7 |
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| 3D View | |
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| PDB Download | Download PDB Predicted by Alphafold2 |
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| PubMed ID | 11932493 |
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