| ID | DRAMP18516 |
|---|---|
| Sequence | KWKSFLKTFKSLKkTVLHTLLKAISS |
| Length | 26 |
| Name | K7D (A12L/A20L peptide derivative) |
| Source | Synthetic construct |
| Activity | Antimicrobial, Antibacterial, Anti-Gram-, Antiplasmodial |
| Pathogen | [Ref.22837667]Cancer cell: HeLa cell (IC50=1.29±0.03 μmol/L) |
| Hemolytic Activity | [Ref.22837667]MHC=10.4±0.04 μmol/L against human red blood cells |
| Cytotoxicity | Not included yet |
| N-terminal Modification | Not included yet |
| C-terminal Modification | Not included yet |
| Linear/Cyclic/Branched | Not included yet |
| Uniprot | |
| PDB | |
| 3D View | |
| PDB Download | Download PDB Predicted by Alphafold2 |
| PubMed ID | 22837667 |
Physicochemical Properties
| Residues | 26 |
|---|---|
| Sequence | KWKSFLKTFKSLKkTVLHTLLKAISS |
| Molecular Weight | 3033.694 |
| Grand Average of Hydropathy | -0.062 |
| Isoelectric Point | 10.778 |
| Charge at pH 7.4 | 6.577 |
| Secondary Structure | Helix: 0.385, Turn: 0.154, Sheet: 0.231 |
| Instability Index | 3.292 |
| Aromaticity | 0.115 |