Basic Information
| ID | DRAMP18515 |
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| Sequence | KWKSFLkTFKSLKKTVLHTLLKAISS |
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| Length | 26 |
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| Name | A12L/A20L (V13KL peptide derivative) |
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| Source | Synthetic construct |
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| Activity | Antimicrobial, Antibacterial, Anti-Gram- |
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| Pathogen | [Ref.17158938]Gram-negative bacteria: Pseudomonas aeruginosa PAO1(MIC=62.5 μg/ml), Pseudomonas aeruginosa WR5 (MIC=125 μg/ml), Pseudomonas aeruginosa PAK (MIC=62.5 μg/ml), Pseudomonas aeruginosa PA14 (MIC=125 μg/ml), Pseudomonas aeruginosa M2 (MIC=62.5 μg/ml), Pseudomonas aeruginosa CP204 (MIC=62.5 μg/ml), The geometric mean of MIC values above six Gram-negative strains (MIC=78.7 μg/ml).##[Ref.22837667]Cancer cell: HeLa cell (IC50=1.71±0.07 μmol/L). |
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| Hemolytic Activity | [Ref.22837667]MHC=8.0 μg/ml, MHC=5.20±0.02 μmol/L against human red blood cells |
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| Cytotoxicity | Not included yet |
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| N-terminal Modification | Not included yet |
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| C-terminal Modification | Not included yet |
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| Linear/Cyclic/Branched | Not included yet |
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| Uniprot |
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| PDB |
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| 3D View | |
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| PDB Download | Download PDB Predicted by Alphafold2 |
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| PubMed ID | 17158938, 22837667 |
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