Basic Information

IDDRAMP03174
SequenceRWCVYAYVRIRGVLVRYRRCW
Length21
NameArenicin-2 (Ar-2; marine polychaeta, animals)
SourceArenicola marina (Lugworm) (Lumbricus marinus)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal
PathogenGram-positive bacterium: Listeria monocytogenes EGD;##Gram-negative bacterium: Escherichia coli ML-35p.##Yeast: Candida albicans 820.
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNo cytotoxicity information found
N-terminal ModificationFree
C-terminal ModificationFree
Linear/Cyclic/BranchedCyclic
Uniprot Q5SC59, P84106
PDB 2JNI, 2L8X
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID15527787, 17935487, 17585874

Physicochemical Properties

Residues21
SequenceRWCVYAYVRIRGVLVRYRRCW
Molecular Weight2774.323
Grand Average of Hydropathy-0.057
Isoelectric Point10.852
Charge at pH 7.45.501
Secondary StructureHelix: 0.524, Turn: 0.048, Sheet: 0.095
Instability Index63.762
Aromaticity0.238

Similar Structure Search

Candidates based on structure

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