Basic Information

IDDRAMP03216
SequenceGIRCPKSWKCKAFKQRVLKRLLAMLRQHAF
Length30
NameOxyopinin-4a (Oxt-4a; spiders, Arthropods, animals)
SourceOxyopes takobius (Lynx spider) (Oxyopes foliiformis)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
Pathogen[Ref.21933345]Gram-positive bacteria: S. aureus (MIC=10 µM) and Bacillus subtilis (MIC=0.5 µM);##Gram-negative bacteria: P. fluorescens (MIC=1 µM) and E. coli (MIC=0.5 µM).
Hemolytic Activity[Ref.21933345] EC50=7 μM against human erythrocytes
CytotoxicityNo cytotoxicity information found
N-terminal ModificationFree
C-terminal ModificationFree
Linear/Cyclic/BranchedCyclic
Uniprot F8J4S0, P86350
PDB 2L3I
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID21933345

Physicochemical Properties

Residues30
SequenceGIRCPKSWKCKAFKQRVLKRLLAMLRQHAF
Molecular Weight3614.453
Grand Average of Hydropathy-0.32
Isoelectric Point11.595
Charge at pH 7.48.532
Secondary StructureHelix: 0.300, Turn: 0.100, Sheet: 0.267
Instability Index37.003
Aromaticity0.1

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