Basic Information
| ID | DRAMP03226 |
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| Sequence | SMWSGMWRRKLKKLRNALKKKLKGE |
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| Length | 25 |
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| Name | M-zodatoxin-Lt1a (M-ZDTX-Lt1a; Latarcin-1, Ltc-1, Ltc1; spiders, Arthropods, animals) |
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| Source | Lachesana tarabaevi (Spider) |
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| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal |
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| Pathogen | [Ref.16735513]Gram-positive bacteria: Arthrobacter globiformis VKM Ac-1112 (MIC=0.5 µM), Bacillus subtilis VKM B-501 (MIC=1.0 µM);##Gram-negative bacteria: Escherichia coli DH5-alpha (MIC=1.0 µM), Escherichia coli MH1 (MIC=0.7µM), Pseudomonas aeruginosa PAO1 (MIC=4.1 µM);##Fungi: Pichia pastoris GS115 (MIC=17 µM), Saccharomyces cerevisiae Y190 (MIC>33 µM). |
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| Hemolytic Activity | [Ref.16735513]20% hemolytic activity at 80 μM against rabbit erythrocytes |
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| Cytotoxicity | Not included yet |
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| N-terminal Modification | Not included yet |
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| C-terminal Modification | Not included yet |
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| Linear/Cyclic/Branched | Not included yet |
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| Uniprot |
Q1ELT9 |
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| PDB |
2PCO |
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| 3D View | |
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| PDB Download | Download PDB Predicted by Alphafold2 |
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| PubMed ID | 16735513, 18293934 |
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