Basic Information

IDDRAMP03464
SequenceGLLNGLALRLGKRALKKIIKRLCR
Length24
NameCryptonin (Insects, animals)
SourceCryptotympana dubia (Korean horse cicada)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal
Pathogen[Ref.18000874]Gram-positive bacteria: Bacillus subtilis KCTC 3086 (MIC=3.12 µg/ml), Staphylococcus aureus KCTC 1928 (MIC=25 µg/ml), Micrococcus luteus KCTC 3063 (MIC=1.56 µg/ml), Staphylococcus aureus (MRSA) (MIC=25 µg/ml), VRE (MIC=25 µg/ml);##Gram-negative bacteria: Escherichia coli K12-594 (MIC=3.12 µg/ml);##Fungi: Candida albicans KCTC 7965 (MIC=50 µg/ml), Candida tropicalis KCTC 1925 (MIC=3.12 µg/ml).
Hemolytic Activity[Ref.18000874]<5% hemolytic activity at 25-200 µg/ml against rat erythrocytes
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot P85028
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID18000874

Physicochemical Properties

Residues24
SequenceGLLNGLALRLGKRALKKIIKRLCR
Molecular Weight2704.421
Grand Average of Hydropathy0.142
Isoelectric Point12
Charge at pH 7.47.523
Secondary StructureHelix: 0.375, Turn: 0.167, Sheet: 0.375
Instability Index24.363
Aromaticity0

Similar Structure Search

Candidates based on structure

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