Basic Information

IDDRAMP03470
SequenceGFGCPWNRYQCHSHCRSIGRLGGYCAGSLRLTCTCYRS
Length38
NameDefensin-1 (American oyster defensin, AOD; molluscs, animals)
SourceCrassostrea virginica (American oyster)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
PathogenGram-positive bacteria: Lactococcus lactis subsp. lactis (MECs=2.4 µg/ml), Staphylococcus aureus (MECs=3 µg/ml);##Gram-negative bacteria: Escherichia coli D31 (MECs=7.6 µg/ml), Vibrio parahaemolyticus (MECs=15 µg/ml).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot P85008
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID16297885

Physicochemical Properties

Residues38
SequenceGFGCPWNRYQCHSHCRSIGRLGGYCAGSLRLTCTCYRS
Molecular Weight4270.863
Grand Average of Hydropathy-0.363
Isoelectric Point9.182
Charge at pH 7.44.476
Secondary StructureHelix: 0.237, Turn: 0.316, Sheet: 0.105
Instability Index55.242
Aromaticity0.132

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