Basic Information

IDDRAMP02426
SequenceGFGCPLNQGACHNHCRSIRRRGGYCSGIIKQTCTCY
Length36
NameDefensin (Varisin A1; Ticks, Arthropods, animals)
SourceDermacentor variabilis (American dog tick)
ActivityAntimicrobial, Antibacterial, Anti-Gram+
PathogenGram-positive bacteria: Bacillus subtilis, Borrelia burgdorferi.
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot Q86QI5
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID11439245, 14563361

Physicochemical Properties

Residues36
SequenceGFGCPLNQGACHNHCRSIRRRGGYCSGIIKQTCTCY
Molecular Weight3961.544
Grand Average of Hydropathy-0.417
Isoelectric Point9.182
Charge at pH 7.44.476
Secondary StructureHelix: 0.194, Turn: 0.306, Sheet: 0.056
Instability Index92.103
Aromaticity0.083

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Candidates based on structure

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