Basic Information

IDDRAMP20878
SequenceMGFGCPEDEYECHNHCKNSVGCRGGYCDAGTLRQRCTCYGCNQKGRSIQE
Length50
NamerVpDef
SourceSynthetic construct
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
Pathogen[Ref.29524591] Gram-positive bacteria: Listeria monocytogenes ATCC 21633 (MIC=75 μg/ml), Bacillu subtilis Lzz-133 (MIC=95 μg/ml), Staphylococcus aureus ATCC 25923 (MIC=120 μg/ml);##Gram-negative bacteria: Escherichia coli O157 ATCC 35150 (MIC=50 μg/ml), Eschericha coli ATCC 10305 (MIC=75 μg/ml), Salmonella enterica ATCC 10467 (MIC=120 μg/ml)
Hemolytic Activity[Ref.29524591] 0% haemolysis at 30 μg/ml, 0% haemolysis at 60 μg/ml, 0% haemolysis at 90 μg/ml, 0% haemolysis at 115 μg/ml, 0.2% haemolysis at 145 μg/ml, 1.5% haemolysis at 175 μg/ml against rabbit red blood cells
Cytotoxicity[Ref.29524591] No cytotoxicity information found
N-terminal ModificationFree
C-terminal ModificationFree
Linear/Cyclic/BranchedLinear
Uniprot
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID29524591

Physicochemical Properties

Residues50
SequenceMGFGCPEDEYECHNHCKNSVGCRGGYCDAGTLRQRCTCYGCNQKGRSIQE
Molecular Weight5566.152
Grand Average of Hydropathy-0.938
Isoelectric Point6.686
Charge at pH 7.4-0.843
Secondary StructureHelix: 0.140, Turn: 0.280, Sheet: 0.140
Instability Index61.004
Aromaticity0.08

Similar Structure Search

Candidates based on structure

Address: No.2699 Qianjin Street, Changchun City, China. Zip Code: 130012. 苏ICP备2021057230号-1.