Basic Information

IDDRAMP02419
SequenceYENPYGCPTDEGKCFDRCNDSEFEGGYCGGSYRATCVCYRT
Length41
NameAmblyomma defensin peptide 2 (ADP-2; Ticks, Arthropods, animals)
SourceAmblyomma hebraeum (Tick)
ActivityAntimicrobial, Antibacterial
PathogenEscherichia coli (MIC=30 µM) and Staphylococcus aureus (MIC=7.5 µM).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNo cytotoxicity information found
N-terminal ModificationFree
C-terminal ModificationFree
Linear/Cyclic/BranchedCyclic
Uniprot
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID14705963

Physicochemical Properties

Residues41
SequenceYENPYGCPTDEGKCFDRCNDSEFEGGYCGGSYRATCVCYRT
Molecular Weight4617.953
Grand Average of Hydropathy-0.929
Isoelectric Point4.441
Charge at pH 7.4-3.599
Secondary StructureHelix: 0.195, Turn: 0.293, Sheet: 0.122
Instability Index12.198
Aromaticity0.171

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