Basic Information
| ID | DRAMP02811 |
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| Sequence | GFGCPNNYQCHRHCKSIPGRCGGYCGGWHRLRCTCYRC |
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| Length | 38 |
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| Name | Defensin MGD-1 (molluscas, animals) |
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| Source | Mytilus galloprovincialis (Mediterranean mussel) |
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| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram- |
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| Pathogen | Gram-positive bacteria: Micrococcus luteus (MIC=0.4 µM)&(MBC=1.5 µM), Bacillus megaterium (MIC=0.8 µM)&(MBC=1.5 µM), Staphylococcus aureus (MIC=0.6 µM)&(MBC=1.2 µM), Staphylococcus epidermidis (MIC=3.1 µM)&(MBC=6.2 µM), Enterococcus fecalis (MIC=0.6 µM)&(MBC=1.2 µM), Aerococcus viridans (MIC=0.4 µM)&(MBC=1.5 µM);##Gram-negative bacteria: Escherichia coli D31 (MIC=1.2 µM)&(MBC=1.2 µM), E. coli 363 (MIC=1.2 µM)&(MBC=1.2 µM), Salmonella newport (MIC>100 µM)&(MBC>100 µM), Vibrio alginolyticus (MIC=50 µM)&(MBC>100 µM), Vibrio harveyi (MIC=50 µM)&(MBC=100 µM), Vibrio metshnikovii (MIC>100 µM)&(MBC>100 µM).##NOTE: MIC=minimal inhibitory concentration; MBC = minimal bactericidal concentration. |
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| Hemolytic Activity | No hemolysis information or data found in the reference(s) presented in this entry |
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| Cytotoxicity | No cytotoxicity information found |
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| N-terminal Modification | Free |
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| C-terminal Modification | Free |
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| Linear/Cyclic/Branched | Cyclic |
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| Uniprot |
P80571, Q9Y0B0 |
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| PDB |
1FJN |
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| 3D View | |
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| PDB Download | Download PDB Predicted by Alphafold2 |
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| PubMed ID | 10564642, 8925841, 11087396 |
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