Basic Information

IDDRAMP03646
SequenceRVKRFWPLVPVAINTVAAGINLYKAIRRK
Length29
NameCathelicidin-3 (CATH-3; Fowlicidin-3; Birds, animals)
SourceGallus gallus (Chicken)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
PathogenGram-negative bacteria: Escherichia coli 25922 (MIC=2 µM), Salmonella typhimurium 14028 (MIC=2 µM), S. typhimurium DT104 700408 (MIC=2 µM), Salmonella enteritidis 13076 (MIC=2 µM), Klebsiella pneumoniae 13883 (MIC=1 µM);##Gram-positive bacteria: Listeria monocytogenes 19115 (MIC=2 µM), Staphylococcus aureus 25923 (MIC=1 µM), S. aureus (MRSA) 43300 (MIC=1 µM), S. aureus (MRSA) BAA-39 (MIC=1 µM).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot Q2IAL6
PDB 2HFR
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID17827276, 16326712, 17229147

Physicochemical Properties

Residues29
SequenceRVKRFWPLVPVAINTVAAGINLYKAIRRK
Molecular Weight3351.046
Grand Average of Hydropathy0.162
Isoelectric Point12
Charge at pH 7.46.547
Secondary StructureHelix: 0.414, Turn: 0.172, Sheet: 0.207
Instability Index47.083
Aromaticity0.103

Similar Structure Search

Candidates based on structure

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