| ID | DRAMP03823 |
|---|---|
| Sequence | ALWKTLLKKVLKA |
| Length | 13 |
| Name | Dermaseptin derivative K4-S4-(1-13) |
| Source | Synthetic construct |
| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram- |
| Pathogen | [Ref.15917541]Gram-negative bacterium: Escherichia coli U16318 (MIC=9-3 µM);##Gram-positive bacterium: Staphylococcus aureus B38302 (MIC=4.5-1.5 µM). |
| Hemolytic Activity | [Ref.15917541]LC50=50 μM against human red blood cells |
| Cytotoxicity | Not included yet |
| N-terminal Modification | Not included yet |
| C-terminal Modification | Not included yet |
| Linear/Cyclic/Branched | Not included yet |
| Uniprot | P80280 |
| PDB | 2DD6 |
| 3D View | |
| PDB Download | Download PDB Predicted by Alphafold2 |
| PubMed ID | 16407175, 15917541 |
Physicochemical Properties
| Residues | 13 |
|---|---|
| Sequence | ALWKTLLKKVLKA |
| Molecular Weight | 1511.935 |
| Grand Average of Hydropathy | 0.446 |
| Isoelectric Point | 10.478 |
| Charge at pH 7.4 | 3.598 |
| Secondary Structure | Helix: 0.462, Turn: 0.000, Sheet: 0.462 |
| Instability Index | 7.854 |
| Aromaticity | 0.077 |