Basic Information

IDDRAMP03870
SequenceRLARIVVIRVAR
Length12
NameBac2A (a linear variant of bovine dodecapeptide)
SourceSynthetic construct
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal
PathogenGram-negative bacteria: Pseudomonas aeruginosa (MIC=50 µg/ml), Escherichia coli (MIC=17 µg/ml), Salmonella (MIC=34 µg/ml);##Gram-positive bacteria: Staphylococcus aureus (MIC=17 µg/ml), Staphylococcus epidermidis (MIC=4 µg/ml), Enterococcus faecalis (MIC=17 µg/ml).##Yeast: Candida albicans (MIC=9 µg/ml).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID16041366, 17052614

Physicochemical Properties

Residues12
SequenceRLARIVVIRVAR
Molecular Weight1421.78
Grand Average of Hydropathy0.917
Isoelectric Point12
Charge at pH 7.43.557
Secondary StructureHelix: 0.500, Turn: 0.000, Sheet: 0.250
Instability Index2.092
Aromaticity0

Similar Structure Search

Candidates based on structure

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