Basic Information

IDDRAMP03857
SequenceRLARRVVIRVAR
Length12
NameR5 (Bac2A variant through single amino acid substitution)
SourceSynthetic construct
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal
PathogenGram-negative bacteria: Pseudomonas aeruginosa (MIC=63 µg/ml), Escherichia coli (MIC=16 µg/ml), Salmonella typhimurium (MIC=31 µg/ml);##Gram-positive bacteria: Staphylococcus aureus (MIC=63 µg/ml), Staphylococcus epidermidis (MIC=16 µg/ml), Enterococcus faecalis (MIC=125 µg/ml).##Yeast: Candida albicans (MIC=125 µg/ml).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID16041366

Physicochemical Properties

Residues12
SequenceRLARRVVIRVAR
Molecular Weight1464.808
Grand Average of Hydropathy0.167
Isoelectric Point12
Charge at pH 7.44.557
Secondary StructureHelix: 0.417, Turn: 0.000, Sheet: 0.250
Instability Index56.9
Aromaticity0

Similar Structure Search

Candidates based on structure

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