Basic Information

IDDRAMP04055
SequenceRRLCRIVWVIRVCRR
Length15
NameBacW2R (cyclic derivative of bactenecin)
SourceSynthetic construct
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
PathogenGram-negative bacteria: Escherichia coli K-12 (MIC=2 µg/ml), Pseudomonas aeruginosa K799 (MIC=2 µg/ml), Salmonella typhimurium 14028s (MIC=2 µg/ml);##Gram-positive bacteria: Staphylococcus aureus ATCC 25923 (MIC=2 µg/ml), Staphylococcus epidermidis C621 (MIC=1 µg/ml), Enterococcus faecalis ATCC 29212 (MIC=2 µg/ml), Listeria monocytogenes (MIC=0.25 µg/ml), Corynebacterium xerosis (MIC=0.25 µg/ml), Streptococcus pyogenes ATCC 19615 (MIC=1 µg/ml), S. mitis (MIC=0.25 µg/ml), Streptococcus pneumoniae ATCC 49619 (MIC=8 µg/ml).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot
PDB
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PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID10223951

Physicochemical Properties

Residues15
SequenceRRLCRIVWVIRVCRR
Molecular Weight1984.491
Grand Average of Hydropathy0.167
Isoelectric Point12
Charge at pH 7.45.508
Secondary StructureHelix: 0.467, Turn: 0.000, Sheet: 0.067
Instability Index74.387
Aromaticity0.067

Similar Structure Search

Candidates based on structure

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