Basic Information

IDDRAMP03862
SequenceRLRRIVVIRVRR
Length12
NameSub2 (Bac2A variant through two amino acids substitution)
SourceSynthetic construct
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal
PathogenGram-negative bacteria: Pseudomonas aeruginosa (MIC=8 µg/ml), Escherichia coli (MIC=2 µg/ml), Salmonella typhimurium (MIC=8 µg/ml);##Gram-positive bacteria: Staphylococcus aureus (MIC=8 µg/ml), Staphylococcus epidermidis (MIC=2 µg/ml), Enterococcus faecalis (MIC=4 µg/ml).##Yeast: Candida albicans (MIC=31 µg/ml).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID16041366

Physicochemical Properties

Residues12
SequenceRLRRIVVIRVRR
Molecular Weight1591.995
Grand Average of Hydropathy-0.133
Isoelectric Point12
Charge at pH 7.45.557
Secondary StructureHelix: 0.500, Turn: 0.000, Sheet: 0.083
Instability Index113.608
Aromaticity0

Similar Structure Search

Candidates based on structure

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