| ID | DRAMP02851 |
|---|---|
| Sequence | RLCRIVVIRVCR |
| Length | 12 |
| Name | Cathelicidin-1 (Bactenecin-1, Bac1; Cyclic dodecapeptide; mammals, animals) |
| Source | Bos taurus (Bovine) |
| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram- |
| Pathogen | Gram-positive bacterium: Staphylococcus aureus (MIC=1-8 µg/ml);##Gram-negative bacterium: Escherichia coli (MIC=8-25 µg/ml). |
| Hemolytic Activity | No hemolysis information or data found in the reference(s) presented in this entry |
| Cytotoxicity | No cytotoxicity information found |
| N-terminal Modification | Free |
| C-terminal Modification | Free |
| Linear/Cyclic/Branched | Cyclic |
| Uniprot | P22226, A5PJA3, Q24JY5 |
| PDB | |
| 3D View | |
| PDB Download | Download PDB Predicted by Alphafold2 |
| PubMed ID | 3290210 |
Physicochemical Properties
| Residues | 12 |
|---|---|
| Sequence | RLCRIVVIRVCR |
| Molecular Weight | 1485.91 |
| Grand Average of Hydropathy | 1.033 |
| Isoelectric Point | 11.526 |
| Charge at pH 7.4 | 3.508 |
| Secondary Structure | Helix: 0.500, Turn: 0.000, Sheet: 0.083 |
| Instability Index | 2.092 |
| Aromaticity | 0 |