| ID | DRAMP04054 |
|---|---|
| Sequence | RLCRIVWVIRVCR |
| Length | 13 |
| Name | BacW (cyclic derivative of bactenecin) |
| Source | Synthetic construct |
| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram- |
| Pathogen | Gram-negative bacteria: Escherichia coli K-12 (MIC=8 µg/ml), Pseudomonas aeruginosa K799 (MIC=4 µg/ml), Salmonella typhimurium 14028s (MIC=4 µg/ml);##Gram-positive bacteria: Staphylococcus aureus ATCC 25923 (MIC=4 µg/ml), Staphylococcus epidermidis C621 (MIC=2 µg/ml), Enterococcus faecalis ATCC 29212 (MIC=8 µg/ml), Listeria monocytogenes (MIC=0.5 µg/ml), Corynebacterium xerosis (MIC=1 µg/ml), Streptococcus pyogenes ATCC 19615 (MIC=2 µg/ml), S. mitis (MIC=1 µg/ml), Streptococcus pneumoniae ATCC 49619 (MIC=16 µg/ml). |
| Hemolytic Activity | No hemolysis information or data found in the reference(s) presented in this entry |
| Cytotoxicity | Not included yet |
| N-terminal Modification | Not included yet |
| C-terminal Modification | Not included yet |
| Linear/Cyclic/Branched | Not included yet |
| Uniprot | |
| PDB | |
| 3D View | |
| PDB Download | Download PDB Predicted by Alphafold2 |
| PubMed ID | 10223951 |
Physicochemical Properties
| Residues | 13 |
|---|---|
| Sequence | RLCRIVWVIRVCR |
| Molecular Weight | 1672.12 |
| Grand Average of Hydropathy | 0.885 |
| Isoelectric Point | 11.526 |
| Charge at pH 7.4 | 3.508 |
| Secondary Structure | Helix: 0.538, Turn: 0.000, Sheet: 0.077 |
| Instability Index | -3.831 |
| Aromaticity | 0.077 |