| ID | dbAMP18504 |
|---|---|
| Sequence | RKCRIVVIRVCR |
| Length | 12 |
| Name | synthetic construct&&dBacK- (cap) (Derived from CAMPs)&&dBacK (Derived from CAMPs)&&D-Cathelicidin-1 [R2k], D-Bactenecin-1 [R2k] |
| Source | synthetic construct |
| Activity | Antibacterial |
| Pathogen | [Ref.31056261] GrµM-positive bacteria: Staphylococcus aureus µMIC=4-8µM), Staphylococcus epideµMidis µMIC=1-2µM), Bacillus subtilis µMIC=1-2µM), Enterococcus faecalis µMIC=4µM);&&GrµM-negative bacteria: Escherichia coli µMIC=1-2µM), SaµMonella typhµMuriµM |
| Hemolytic Activity | Not included yet |
| Cytotoxicity | Not included yet |
| N-terminal Modification | Not included yet |
| C-terminal Modification | Not included yet |
| Linear/Cyclic/Branched | Not included yet |
| Uniprot | |
| PDB | |
| 3D View | |
| PDB Download | Download PDB Predicted by Alphafold2 |
| PubMed ID | 31056261, 31056261, 31056261 |
Physicochemical Properties
| Residues | 12 |
|---|---|
| Sequence | RKCRIVVIRVCR |
| Molecular Weight | 1500.924 |
| Grand Average of Hydropathy | 0.392 |
| Isoelectric Point | 11.542 |
| Charge at pH 7.4 | 4.506 |
| Secondary Structure | Helix: 0.417, Turn: 0.000, Sheet: 0.000 |
| Instability Index | 2.092 |
| Aromaticity | 0 |