Basic Information

IDDRAMP04057
SequenceRLSRIVVIRVCR
Length12
NameLin BacS-NH2 (linear derivative of bactenecin)
SourceSynthetic construct
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
PathogenGram-negative bacteria: Escherichia coli K-12 (MIC=4 µg/ml), Pseudomonas aeruginosa K799 (MIC=16 µg/ml), Salmonella typhimurium 14028s (MIC>64 µg/ml);##Gram-positive bacteria: Staphylococcus aureus ATCC 25923 (MIC=16 µg/ml), Staphylococcus epidermidis C621 (MIC=2 µg/ml), Enterococcus faecalis ATCC 29212 (MIC=16 µg/ml), Listeria monocytogenes (MIC=0.5 µg/ml), Corynebacterium xerosis (MIC=0.5 µg/ml), Streptococcus pyogenes ATCC 19615 (MIC=8 µg/ml), S. mitis (MIC=0.5 µg/ml), Streptococcus pneumoniae ATCC 49619 (MIC=8 µg/ml).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID10223951

Physicochemical Properties

Residues12
SequenceRLSRIVVIRVCR
Molecular Weight1469.844
Grand Average of Hydropathy0.758
Isoelectric Point12
Charge at pH 7.43.533
Secondary StructureHelix: 0.500, Turn: 0.083, Sheet: 0.083
Instability Index18.142
Aromaticity0

Similar Structure Search

Candidates based on structure

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