Basic Information

IDDRAMP03926
SequenceGWLRKLGAVLKVLTT
Length15
NameCecropin B (1-7)-melittin (4-11)hybrid peptide (CBM)
SourceSynthetic construct
ActivityAntimicrobial, Antibacterial
Pathogen[Ref.20111863]Escherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa, Klebsiella pneumoniae, Bacillus subtilis, Bacillus thuringiensis, Salmonella derby.
Hemolytic Activity[Ref.20111863]0.05% hemolytic activity at 5 mg/kg, 0.14% hemolytic activity at 10 mg/kg in vivo
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID20111863

Physicochemical Properties

Residues15
SequenceGWLRKLGAVLKVLTT
Molecular Weight1655.036
Grand Average of Hydropathy0.667
Isoelectric Point11.166
Charge at pH 7.42.552
Secondary StructureHelix: 0.467, Turn: 0.133, Sheet: 0.333
Instability Index15.987
Aromaticity0.067

Similar Structure Search

Candidates based on structure

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