Basic Information
| ID | DRAMP04003 |
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| Sequence | ILGKIWKIKKLF |
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| Length | 12 |
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| Name | [K7, P8, K11]-IsCT (IsCT analog through amino acids substitution) |
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| Source | Synthetic construct |
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| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram- |
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| Pathogen | [Ref.15369808]Gram-negative bacteria: Escherichia coli KCTC 1682 (MIC=2 µM), Pseudomonas aeruginosa KCTC 1637 (MIC=2 µM), Salmonella typhimurium KCTC 1926 (MIC=1 µM);##Gram-positive bacteria: Staphylococcus epidermidis KCTC 1917 (MIC=1 µM), Staphylococcus aureus KCTC 1621 (MIC=2 µM);##Antibiotic-resistant bacteria: Methicillin-resistant Staphylococcus aureus (MRSA) CCARM 3001 (MIC=1 µM), multidrug-resistant Pseudomonas aeruginosa (MDRPA) (CCARM 3543) (MIC=1 µM) and multidrug-resistant Pseudomonas aeruginosa (MDRPA) CCARM 2095 (MIC=1 µM). |
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| Hemolytic Activity | [Ref.15369808]Non-hemolytic activity |
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| Cytotoxicity | Not included yet |
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| N-terminal Modification | Not included yet |
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| C-terminal Modification | Not included yet |
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| Linear/Cyclic/Branched | Not included yet |
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| Uniprot |
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| PDB |
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| 3D View | |
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| PDB Download | Download PDB Predicted by Alphafold2 |
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| PubMed ID | 15369808 |
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