| ID | DRAMP04205 |
|---|---|
| Sequence | RWFKIQLQIRRWKNKK |
| Length | 16 |
| Name | PenShufLeu |
| Source | Synthetic construct |
| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram- |
| Pathogen | [Ref.23085001] Gram-positive bacteria : Staphylococcus aureus(ATCC 33591)(MIC=16 μM);##Gram-negative bacteria : Escherichia coli(ATCC 25922)(MIC=32 μM) |
| Hemolytic Activity | [Ref.23085001] HC50=65±2.5 μM against human red blood cells |
| Cytotoxicity | Not included yet |
| N-terminal Modification | Not included yet |
| C-terminal Modification | Not included yet |
| Linear/Cyclic/Branched | Not included yet |
| Uniprot | |
| PDB | |
| 3D View | |
| PDB Download | Download PDB Predicted by Alphafold2 |
| PubMed ID | 23085001 |
Physicochemical Properties
| Residues | 16 |
|---|---|
| Sequence | RWFKIQLQIRRWKNKK |
| Molecular Weight | 2228.689 |
| Grand Average of Hydropathy | -1.612 |
| Isoelectric Point | 12 |
| Charge at pH 7.4 | 6.547 |
| Secondary Structure | Helix: 0.375, Turn: 0.062, Sheet: 0.062 |
| Instability Index | 137.25 |
| Aromaticity | 0.188 |