Basic Information

IDDRAMP18444
SequenceRYPAVGYT
Length8
NameLacrain (myriapods, arthropods, invertebrates, animals)
SourceBrazilian centipede, Scolopendra viridicornis
ActivityAntimicrobial, Antibacterial, Anti-Gram-
Pathogen[Ref.27451089]Gram-negative bacteria : Pseudomonas aeruginosa ATCC 27853 (MIC=5.8 μg/ml;MBC=11.6 μg/ml), Alcaligenes faecalis ATCC 8750 (MIC=5.8 μg/ml;MBC=5.8 μg/ml), Serratia marcescens ATCC 4112 (MIC=5.8 μg/ml;MBC=5.8 μg/ml), Enterobacter cloacae β-12 (MIC=2.9 μg/ml;MBC=2.9 μg/ml), Salmonella serovars (MIC=5.8 μg/ml;MBC=11.6 μg/ml), Salmonella enterica subsp. arizonae (MIC=5.8 μg/ml;MBC=5.8 μg/ml), Escherichia coli SBS363 (MIC=5.8 μg/ml;MBC=5.8 μg/ml), Escherichia coli D31 (MIC=5.8 μg/ml;MBC=5.8 μg/ml)
Hemolytic Activity[Ref.27451089] 0% hemolysis at 0.5-500 μM against human red blood cells
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID27451089

Physicochemical Properties

Residues8
SequenceRYPAVGYT
Molecular Weight926.027
Grand Average of Hydropathy-0.475
Isoelectric Point8.59
Charge at pH 7.40.552
Secondary StructureHelix: 0.375, Turn: 0.250, Sheet: 0.125
Instability Index6.987
Aromaticity0.25

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