| ID | DRAMP18504 |
|---|---|
| Sequence | FSEAIKKIIDFLGEGLFDIIKKIAESF |
| Length | 27 |
| Name | E(AU)2 (Aurein 1.2 peptide derivative) |
| Source | Litoria raniformis (Southern bell frog) |
| Activity | Antimicrobial, Antibacterial, Anti-Gram- |
| Pathogen | [Ref.23519707]Gram-negative bacterium: Escherichia coli (MIC=128 μmol/L) |
| Hemolytic Activity | [Ref.23519707]~5% hemolysis at 128μmol/L, 0% hemolysis at 4 -32μmol/L against human red blood cells. |
| Cytotoxicity | Not included yet |
| N-terminal Modification | Not included yet |
| C-terminal Modification | Not included yet |
| Linear/Cyclic/Branched | Not included yet |
| Uniprot | |
| PDB | |
| 3D View | |
| PDB Download | Download PDB Predicted by Alphafold2 |
| PubMed ID | 23519707 |
Physicochemical Properties
| Residues | 27 |
|---|---|
| Sequence | FSEAIKKIIDFLGEGLFDIIKKIAESF |
| Molecular Weight | 3072.59 |
| Grand Average of Hydropathy | 0.515 |
| Isoelectric Point | 4.939 |
| Charge at pH 7.4 | -1.448 |
| Secondary Structure | Helix: 0.444, Turn: 0.148, Sheet: 0.259 |
| Instability Index | 10.304 |
| Aromaticity | 0.148 |