Basic Information

IDDRAMP18650
SequenceFQWQRNMRKVR
Length11
NameHLP7 (HLP2 peptide derivative)
SourceSynthetic construct
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
Pathogen[Ref.9596699] Gram-negative bacteria: Escherichia coli NCTC 8007 (MIC=18 μM), Escherichia coli NCTC 10418 (MIC=40 μM);##Gram-negative bacterium: Staphylococcus aureus (MIC=14 μM);##Clinical isolates: Acinetobacter sp. (MIC=0.3 μM), Klebsiella sp. strain 3105 (MIC=80 μM), Providencia stuartii (MIC=110 μM).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot
PDB
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PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID9596699

Physicochemical Properties

Residues11
SequenceFQWQRNMRKVR
Molecular Weight1548.816
Grand Average of Hydropathy-1.809
Isoelectric Point12
Charge at pH 7.43.555
Secondary StructureHelix: 0.273, Turn: 0.091, Sheet: 0.091
Instability Index5.736
Aromaticity0.182

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