Basic Information
| ID | DRAMP21018 |
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| Sequence | AIGSILGALAKGLPTLRSWIKNR |
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| Length | 23 |
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| Name | A (I17R) (Derived from AR-23) |
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| Source | Synthetic construct |
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| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram- |
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| Pathogen | [Ref.27271216]Gram-positive bacteria : Staphylococcuss aureus (MIC=25 μM), Staphylococcus epidermidis (MIC=6.25 μM), Bacillus subtilis (MIC=3.13 μM);##Gram-negative bacteria : Escherichia coli (MIC=12.5 μM), Pseudomonas aeruginosa (MIC=12.5 μM), Klebsiella pneumoniae (MIC=25 μM) |
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| Hemolytic Activity | [Ref.27271216] 10% hemolysis at 20 μM , 15% hemolysis at 40 μM , 20% hemolysis at 60 μM , 30% hemolysis at 80 μM , 35% hemolysis at 100 μM against human red blood cells |
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| Cytotoxicity | [Ref.27271216] In L929 cells, the cell viability is 85%, 68%, 21% and 6.6% at peptide concentrations of 6.25, 12.5, 25 and 50 μM. |
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| N-terminal Modification | Free |
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| C-terminal Modification | Amidation |
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| Linear/Cyclic/Branched | Linear |
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| Uniprot |
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| PDB |
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| 3D View | |
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| PDB Download | Download PDB Predicted by Alphafold2 |
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| PubMed ID | 27271216 |
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