Basic Information
| ID | DRAMP21022 |
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| Sequence | RIGSILGRLAKGLPTLKSWIKNR |
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| Length | 23 |
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| Name | A (A1R, A8R, I17K) (Derived from AR-23) |
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| Source | Synthetic construct |
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| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram- |
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| Pathogen | [Ref.27271216]Gram-positive bacteria : Staphylococcuss aureus (MIC=100 μM), Staphylococcus epidermidis (MIC=6.25 μM), Bacillus subtilis (MIC=12.5 μM);##Gram-negative bacteria : Escherichia coli (MIC=12.5 μM), Pseudomonas aeruginosa (MIC=12.5 μM), Klebsiella pneumoniae (MIC=12.5 μM) |
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| Hemolytic Activity | [Ref.27271216] 0% hemolysis at 40 μM , 1% hemolysis at 60 μM , 2% hemolysis at 80 μM , 2% hemolysis at 100 μM against human red blood cells |
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| Cytotoxicity | [Ref.27271216] In L929 cells, the cell viability is 96%, 95%, 92%, 68% and 31.4% at peptide concentrations of 3.12, 6.25, 12.5, 25 and 50 μM |
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| N-terminal Modification | Free |
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| C-terminal Modification | Amidation |
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| Linear/Cyclic/Branched | Linear |
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| Uniprot |
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| PDB |
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| 3D View | |
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| PDB Download | Download PDB Predicted by Alphafold2 |
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| PubMed ID | 27271216 |
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