Basic Information
| ID | DRAMP03002 |
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| Sequence | GIGAVLKVLTTGLPALISWIKRKRQQ |
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| Length | 26 |
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| Name | Melittin (Allergen Api m 3; Allergen Api m III; Insects, animals) |
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| Source | Apis mellifera (Honeybee) |
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| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal |
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| Pathogen | [Ref.29783753] Gram-positive bacteria: Staphylococcus aureus ATCC 29213 (MIC=2 μM), Listeria monocytogenes CMCC 54004 (MIC=1 μM);##Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=1 μM), Escherichia coli UB 1005 (MIC=2 μM), Salmonella pullorum C7913 (MIC=8 μM), Salmonella enterica subsp enterica CMCC 50071 (MIC=2 μM) |
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| Hemolytic Activity | [Ref.29859288] MHC=1 μM against human red blood cell.##[Ref.2978375] 46.80% hemolysis at 2μM against human red blood cell##[Ref.20472009] Wild-type melittin:AVG ± S.D.(%)=0.077±0.002 (35) against human red blood cell. |
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| Cytotoxicity | Not included yet |
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| N-terminal Modification | Not included yet |
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| C-terminal Modification | Not included yet |
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| Linear/Cyclic/Branched | Not included yet |
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| Uniprot |
P01501, P01503 |
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| PDB |
2MLT, 3QRX, 1BH1 |
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| 3D View | |
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| PDB Download | Download PDB Predicted by Alphafold2 |
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| PubMed ID | 29859288, 29783753, 6309516, 20472009, 20403370, 5300771 |
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