| ID | DRAMP03816 |
|---|---|
| Sequence | GILDTLKQFAKGVGKFLVKGAAQ |
| Length | 23 |
| Name | D16F-N23 (single amino acid substitution) |
| Source | Synthetic construct |
| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram- |
| Pathogen | Gram-positive bacterium: Bacillus subtilis (MIC=25 µg/ml);##Gram-negative bacteria: Klebsiella pneumoniae (MIC=100 µg/ml), Shigella dysentariae (MIC=50 µg/ml), Pseudomonas aeruginosa (MIC=200 µg/ml), Eshchericia coli (MIC=25 µg/ml). |
| Hemolytic Activity | No hemolysis information or data found in the reference(s) presented in this entry |
| Cytotoxicity | Not included yet |
| N-terminal Modification | Not included yet |
| C-terminal Modification | Not included yet |
| Linear/Cyclic/Branched | Not included yet |
| Uniprot | |
| PDB | |
| 3D View | |
| PDB Download | Download PDB Predicted by Alphafold2 |
| PubMed ID | 12199716 |
Physicochemical Properties
| Residues | 23 |
|---|---|
| Sequence | GILDTLKQFAKGVGKFLVKGAAQ |
| Molecular Weight | 2389.833 |
| Grand Average of Hydropathy | 0.3 |
| Isoelectric Point | 10.001 |
| Charge at pH 7.4 | 2.548 |
| Secondary Structure | Helix: 0.348, Turn: 0.174, Sheet: 0.261 |
| Instability Index | -8.687 |
| Aromaticity | 0.087 |