Basic Information

IDDRAMP18194
SequenceGGLKKLGKKLEGAGKRVFKASEKALPVVVGIKAIGK
Length36
NameAAEL000598-PA
SourceAedes aegypti (Yellowfever mosquito) (Culex aegypti)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
PathogenGram-negative (including drug-resistent): E. coli (MIC 2-4 ug/mL), P. aeruginosa (MIC 1-4 ug/mL), A. baumannii (MIC 1-2 ug/mL), K. pneunomiae (MIC 1-2 ug/mL).##No antibacterial effects of the peptide were observed against different isolates of Gram-positive S. aureus, E. faecalis and E. faecium strains showing MIC values over 32. (Pubmed:25162372)
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot Q17NR1
PDB 2MMM
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID17510324, 25162372

Physicochemical Properties

Residues36
SequenceGGLKKLGKKLEGAGKRVFKASEKALPVVVGIKAIGK
Molecular Weight3676.486
Grand Average of Hydropathy-0.022
Isoelectric Point10.535
Charge at pH 7.47.537
Secondary StructureHelix: 0.306, Turn: 0.250, Sheet: 0.278
Instability Index10.497
Aromaticity0.028

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Candidates based on structure

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