Basic Information

IDDRAMP02268
SequenceGWASKIGQTLGKIAKVGLKELIQPK
Length25
NameXenopsin precursor fragment (XPF; Frogs, amphibians, animals)
SourceXenopus laevis (African clawed frog)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal
PathogenGram-negative bacteria: Escherichia coli (MIC=16-31 µg/ml), K. Pneumonae (MIC=62-125 µg/ml), Pseudomonas aeruginosa (MIC=125-250 µg/ml);##Gram-positive bacteria: Staphylococcus aureus (MIC=250-500 µg/ml), Streptococcus faecalis (MIC=250-500 µg/ml).##Yeast: Candida albicans (MIC=250-500 µg/ml).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot P07198
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID1717472

Physicochemical Properties

Residues25
SequenceGWASKIGQTLGKIAKVGLKELIQPK
Molecular Weight2664.193
Grand Average of Hydropathy-0.116
Isoelectric Point10.177
Charge at pH 7.43.546
Secondary StructureHelix: 0.320, Turn: 0.240, Sheet: 0.240
Instability Index-4.148
Aromaticity0.04

Similar Structure Search

Candidates based on structure

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