| ID | DRAMP18589 |
|---|---|
| Sequence | GWLDVAKKIGKAAFNVAKNFLFNKAVNFAAKGIKKAVDLWG |
| Length | 41 |
| Name | DSE (Ctx-Ha peptide derivative) |
| Source | Synthetic construct |
| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Anitifungal |
| Pathogen | [Ref.22391524]Gram-positive bacterium: Staphylococcus aureus (MIC=8.9 μmol/L; MMC=13.3 μmol/L);##Gram-negative bacterium: Escherichia coli (MIC=3.3 μmol/L; MMC=13.3 μmol/L);##Fungi: Candida albicans (MIC=53.3 μmol/L; MMC=53.3 μmol/L) |
| Hemolytic Activity | [Ref.22391524]HC50=0.6±0.1 μmol/L against human red blood cells |
| Cytotoxicity | Not included yet |
| N-terminal Modification | Not included yet |
| C-terminal Modification | Not included yet |
| Linear/Cyclic/Branched | Not included yet |
| Uniprot | |
| PDB | |
| 3D View | |
| PDB Download | Download PDB Predicted by Alphafold2 |
| PubMed ID | 22391524 |
Physicochemical Properties
| Residues | 41 |
|---|---|
| Sequence | GWLDVAKKIGKAAFNVAKNFLFNKAVNFAAKGIKKAVDLWG |
| Molecular Weight | 4450.234 |
| Grand Average of Hydropathy | 0.176 |
| Isoelectric Point | 10.222 |
| Charge at pH 7.4 | 5.538 |
| Secondary Structure | Helix: 0.366, Turn: 0.195, Sheet: 0.268 |
| Instability Index | 3.446 |
| Aromaticity | 0.146 |