Basic Information
| ID | DRAMP21093 |
|---|
| Sequence | RFRRLRwKTRwRLKKI |
|---|
| Length | 16 |
|---|
| Name | PRW4-d (Derived from PRW4) |
|---|
| Source | Synthetic construct |
|---|
| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram- |
|---|
| Pathogen | [Ref.25735802] Gram-positive bacteria : Staphylococcus aureus 29213(MIC=8 μM), Staphylococcus epidermidis 12228(MIC=16 μM), Enterococcus faecalis 29212(MIC=4 μM);##Gram-negative bacteria : Escherichia coli 25922(MIC=4 μM), Escherichia coli 1005(MIC=8 μM), Salmonella typhimurium 7731(MIC=4 μM) |
|---|
| Hemolytic Activity | [Ref.25735802] MHC5>256 μM against human red blood cells |
|---|
| Cytotoxicity | [Ref.25735802] The peptide exhibited no cytoxicity against HaCaT cells in the range of 0/25-256 μM. |
|---|
| N-terminal Modification | Free |
|---|
| C-terminal Modification | Amidation |
|---|
| Linear/Cyclic/Branched | Linear |
|---|
| Uniprot |
|
|---|
| PDB |
|
|---|
| 3D View | |
|---|
| PDB Download | Download PDB Predicted by Alphafold2 |
|---|
| PubMed ID | 25735802 |
|---|
