| ID | DRAMP21117 |
|---|---|
| Sequence | KWCFRVCRRGICYRRCR |
| Length | 17 |
| Name | Y8R (Derived from tachyplesin I) |
| Source | Synthetic construct |
| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram- |
| Pathogen | [Ref.26549611] Gram-positive bacteria : Staphylococcus aureus 209P(MIC=3.13 μM);##Gram-negative bacteria : Escherichia coli C600(MIC=1.56 μM), Pseudomonas aeruginosa PAO1(MIC=6.25 μM) |
| Hemolytic Activity | [Ref.26549611] MHC2=195 μM against human red blood cells |
| Cytotoxicity | [Ref.26549611] No cytotoxicity information found. |
| N-terminal Modification | Free |
| C-terminal Modification | Amidation |
| Linear/Cyclic/Branched | Linear |
| Uniprot | |
| PDB | |
| 3D View | |
| PDB Download | Download PDB Predicted by Alphafold2 |
| PubMed ID | 26549611 |
Physicochemical Properties
| Residues | 17 |
|---|---|
| Sequence | KWCFRVCRRGICYRRCR |
| Molecular Weight | 2261.77 |
| Grand Average of Hydropathy | -0.706 |
| Isoelectric Point | 10.787 |
| Charge at pH 7.4 | 6.454 |
| Secondary Structure | Helix: 0.294, Turn: 0.059, Sheet: 0.000 |
| Instability Index | 56.865 |
| Aromaticity | 0.176 |