Basic Information
| ID | DRAMP21137 |
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| Sequence | RVVRPVVQVVKQKVR |
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| Length | 15 |
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| Name | GNU5 (De novo synthesis) |
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| Source | Synthetic construct |
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| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal |
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| Pathogen | [Ref.23946320] Gram-positive bacteria : Bacillus subtilis(MIC=16 mg/L), Enterococcus faecalis(MIC=8 mg/L), Micrococcus luteus(MIC=2 mg/L), Staphylococcus aureus(MIC=4 mg/L);##Gram-negative bacteria : Escherichia coli(MIC=32 mg/L), Pseudomonas aeruginosa(MIC=8 mg/L), Salmonella typhimurium(MIC>64 mg/L);##Fungi : Candida albicans(MIC=2 mg/L), Cryptococcus neoformans(MIC=2 mg/L), Saccharomyces cerevisiae(MIC=2 mg/L) |
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| Hemolytic Activity | [Ref.23946320] 0% hemolysis at 140 mg/L against human red blood cells |
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| Cytotoxicity | [Ref.23946320] The cell viability of hPBMCs is at peptide concentrations of 4, 8, 16, 32, 64 μg/ml |
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| N-terminal Modification | Free |
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| C-terminal Modification | Free |
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| Linear/Cyclic/Branched | Linear |
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| Uniprot |
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| PDB |
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| 3D View | |
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| PDB Download | Download PDB Predicted by Alphafold2 |
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| PubMed ID | 23946320 |
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