Basic Information

IDDRAMP01364
SequenceGLFGVLAKVAAHVVPAIAEHF
Length21
NameMaculatin-1.1 (Frogs, amphibians, animals)
SourceLitoria genimaculata (Green-eyed tree frog)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal, Antiviral
Pathogen[Ref.15203252]Gram-positive bacteria: Bacillus cereus (MIC=25 µg/ml), Bacillus cereus (MIC=3 µg/ml), Listeria innocua (MIC=100 µg/ml), Micrococcus luteus (MIC=12 µg/ml), Staphylococcus aureus (MIC=6 µg/ml), Staphylococcus epidermidis (MIC=12 µg/ml), Streptococcus uberis (MIC=3 µg/ml);##Gram-negative bacterium: Pasteurella multocida (MIC=50 µg/ml). ##[Ref.16140737]Virus:HIV:inhibit 50% of PBS-treated HIV infection of T cells(IC50=11.3 μM).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNo cytotoxicity information found in the reference(s) presented
N-terminal ModificationFree
C-terminal ModificationAmidation
Linear/Cyclic/BranchedLinear
Uniprot P82066
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID16140737, 9620615, 15203252

Physicochemical Properties

Residues21
SequenceGLFGVLAKVAAHVVPAIAEHF
Molecular Weight2146.532
Grand Average of Hydropathy1.3
Isoelectric Point6.921
Charge at pH 7.4-0.371
Secondary StructureHelix: 0.429, Turn: 0.143, Sheet: 0.381
Instability Index11.252
Aromaticity0.095

Similar Structure Search

Candidates based on structure

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