Basic Information

IDDRAMP01551
SequenceGLLGVLGSVAKHVLPHVVPVIAEHL
Length25
NameCaerin-1.2 (Frogs, amphibians, animals)
SourceLitoria caerulea (Australian frog)
ActivityAntimicrobial, Antibacterial,Antiviral
Pathogen[Ref.26026377]Virus:HIV: inhibition of HIV Pseudovirus (PsV) infection in CD4+ T cells(IC50=5 µM).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity[Ref.26026377]CD4+ T Lymphocytes:50% cell death at 22 µM.
N-terminal ModificationFree
C-terminal ModificationAmidation
Linear/Cyclic/BranchedLinear
Uniprot P56227
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID26026377, PubMed ID is not available

Physicochemical Properties

Residues25
SequenceGLLGVLGSVAKHVLPHVVPVIAEHL
Molecular Weight2555.068
Grand Average of Hydropathy1.204
Isoelectric Point7.024
Charge at pH 7.4-0.334
Secondary StructureHelix: 0.480, Turn: 0.240, Sheet: 0.320
Instability Index29.696
Aromaticity0

Similar Structure Search

Candidates based on structure

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