Basic Information

IDDRAMP01553
SequenceGLLSSLSSVAKHVLPHVVPVIAEHL
Length25
NameCaerin-1.4 (Frogs, amphibians, animals)
SourceLitoria caerulea (Green tree frog) (also Litoria gilleni) (Centralian tree frog)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
PathogenGram-positive bacteria: Bacillus cereus (MIC=50 µg/ml), Leuconostoc lactis (MIC=12 µg/ml), Listeria innocua (MIC=100 µg/ml), Micrococcus luteus (MIC=0.4 µg/ml), Staphylococcus aureus (MIC=100 µg/ml), Staphylococcus epidermis (MIC=25 µg/ml), Streptococcus uberis (MIC=100 µg/ml);##Gram-negative bacteria: Escherichia coli (MIC=50 µg/ml), Pasteurella multocida (MIC=25 µg/ml). (Ref.2)
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity[Ref.15203252]No cytotoxicity information found
N-terminal ModificationFree
C-terminal ModificationAmidation
Linear/Cyclic/BranchedLinear
Uniprot P62544, P56229, P62545, P56229
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID15203252, PubMed ID is not available

Physicochemical Properties

Residues25
SequenceGLLSSLSSVAKHVLPHVVPVIAEHL
Molecular Weight2603.067
Grand Average of Hydropathy0.972
Isoelectric Point7.024
Charge at pH 7.4-0.334
Secondary StructureHelix: 0.440, Turn: 0.280, Sheet: 0.320
Instability Index45.104
Aromaticity0

Similar Structure Search

Candidates based on structure

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