Basic Information

IDDRAMP01556
SequenceGLFSVLGAVAKHVLPHVVPVIAEKL
Length25
NameCaerin-1.6 (Frogs, amphibians, animals)
SourceLitoria xanthomera (Orange-thighed frog) (Litoria chloris)
ActivityAntimicrobial, Antibacterial,Antiviral
Pathogen[Ref.26026377]Virus:HIV: inhibition of HIV Pseudovirus (PsV) infection in CD4+ T cells(IC50=2 µM).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity[Ref.26026377]Human endocervical cells End1/E6E7:50% cell death at 10 µM.
N-terminal ModificationFree
C-terminal ModificationAmidation
Linear/Cyclic/BranchedLinear
Uniprot P62546, P56231, P81249, P62547
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID26026377, 9230483, 9204574, 9516047

Physicochemical Properties

Residues25
SequenceGLFSVLGAVAKHVLPHVVPVIAEKL
Molecular Weight2594.144
Grand Average of Hydropathy1.224
Isoelectric Point8.606
Charge at pH 7.40.627
Secondary StructureHelix: 0.480, Turn: 0.200, Sheet: 0.320
Instability Index25.92
Aromaticity0.04

Similar Structure Search

Candidates based on structure

Address: No.2699 Qianjin Street, Changchun City, China. Zip Code: 130012. 苏ICP备2021057230号-1.