Basic Information
| ID | DRAMP01549 |
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| Sequence | GLLSVLGSVAKHVLPHVVPVIAEHL |
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| Length | 25 |
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| Name | Caerin-1.1 (Frogs, amphibians, animals) |
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| Source | Litoria splendida (Magnificent tree frog) (Litoria gilleni) (Litoria caerulea) |
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| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antiviral |
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| Pathogen | [Ref.15203252]Gram-positive bacteria: Bacillus cereus (MIC=50 µg/ml), Leuconostoc lactis (MIC=1.5 µg/ml), Listeria innocua (MIC=25 µg/ml), Micrococcus luteus (MIC=12.5 µg/ml), Staphylococcus aureus (MIC=3-12 µg/ml), Staphylococcus epidermis (MIC=12.5 µg/ml), Streptococcus uberis (MIC=12.5 µg/ml);##Gram-negative bacterium: Pasteurella multocida (MIC=25 µg/ml).##[Ref.16140737]Virus:HIV:inhibit 50% of PBS-treated HIV infection of T cells(IC50=7.8 μM);inhibition of HIV transfer by dendritic cells to T cells(IC50=12.6 μM) |
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| Hemolytic Activity | No hemolysis information or data found in the reference(s) presented in this entry |
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| Cytotoxicity | No cytotoxicity information found in the reference(s) presented |
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| N-terminal Modification | Free |
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| C-terminal Modification | Amidation |
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| Linear/Cyclic/Branched | Linear |
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| Uniprot |
P62568, P62569, Q800R2, P56226 |
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| PDB |
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| 3D View | |
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| PDB Download | Download PDB Predicted by Alphafold2 |
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| PubMed ID | 16140737, 9266696, 12709067, 15203252 |
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