Basic Information

IDDRAMP01552
SequenceGLLSVLGSVAQHVLPHVVPVIAEHL
Length25
NameCaerin-1.3 (Frogs, amphibians, animals)
SourceLitoria caerulea (Australian frog)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
PathogenGram-positive bacteria: Bacillus cereus (MIC=50 µg/ml), Leuconostoc lactis (MIC=3 µg/ml), Listeria innocua (MIC=50 µg/ml), Micrococcus luteus (MIC=25 µg/ml), Staphylococcus aureus (MIC=6-12 µg/ml), Staphylococcus epidermis (MIC=12 µg/ml), Streptococcus uberis (MIC=25 µg/ml);##Gram-negative bacterium: Pasteurella multocida (MIC=50 µg/ml). (Ref.2)
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity[Ref.15203252]No cytotoxicity information found
N-terminal ModificationFree
C-terminal ModificationAmidation
Linear/Cyclic/BranchedLinear
Uniprot P56228
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID15203252, PubMed ID is not available

Physicochemical Properties

Residues25
SequenceGLLSVLGSVAQHVLPHVVPVIAEHL
Molecular Weight2585.051
Grand Average of Hydropathy1.204
Isoelectric Point6.257
Charge at pH 7.4-1.332
Secondary StructureHelix: 0.480, Turn: 0.240, Sheet: 0.320
Instability Index29.696
Aromaticity0

Similar Structure Search

Candidates based on structure

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