Basic Information
| ID | DRAMP01577 |
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| Sequence | GLLSVLGSVAKHVLPHVVPVIAEKL |
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| Length | 25 |
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| Name | Caerin-1.10 (Frogs, amphibians, animals) |
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| Source | Litoria rothii (Roth's tree frog); also Litoria splendida (Magnificent tree frog) |
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| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-,Antiviral |
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| Pathogen | [Ref.10601876]Gram-positive bacteria: Leuconostoc lactis (MIC=6 µg/ml), Listeria innocua (MIC=50 µg/ml), Micrococcus luteus (MIC=25 µg/ml), Streptococcus uberis (MIC=50 µg/ml), Staphylococcus epidermidis (MIC=100 µg/ml);##Gram-negative bacterium: Pasteurella multocida (MIC=100 µg/ml).##[Ref.26026377]Virus:HIV: inhibition of HIV Pseudovirus (PsV) infection in CD4+ T cells(IC50=2.5 µM). |
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| Hemolytic Activity | No hemolysis information or data found in the reference(s) presented in this entry |
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| Cytotoxicity | [Ref.26026377]CD4+ T Lymphocytes:50% cell death at 22 µM. |
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| N-terminal Modification | Free |
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| C-terminal Modification | Amidation |
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| Linear/Cyclic/Branched | Linear |
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| Uniprot |
P86502, P82104 |
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| PDB |
|
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| 3D View | |
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| PDB Download | Download PDB Predicted by Alphafold2 |
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| PubMed ID | 26026377, 16124032, 10601876 |
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