Basic Information
| ID | DRAMP01555 |
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| Sequence | GLLSVLGSVVKHVIPHVVPVIAEHL |
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| Length | 25 |
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| Name | Caerin-1.5 (Frogs, amphibians, animals) |
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| Source | Litoria caerulea (Green tree frog) |
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| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-,Antiviral |
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| Pathogen | [Ref.15203252]Gram-positive bacteria: Bacillus cereus (MIC=50 µg/ml), Leuconostoc lactis (MIC=3 µg/ml), Listeria innocua (MIC=50 µg/ml), Micrococcus luteus (MIC=12 µg/ml), Staphylococcus aureus (MIC=25 µg/ml), Staphylococcus epidermis (MIC=25 µg/ml), Streptococcus uberis (MIC=50 µg/ml);##Gram-negative bacterium: Pasteurella multocida (MIC=25 µg/ml). ##[Ref.26026377]Virus:HIV: inhibition of HIV Pseudovirus (PsV) infection in CD4+ T cells(IC50=3 µM). |
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| Hemolytic Activity | No hemolysis information or data found in the reference(s) presented in this entry |
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| Cytotoxicity | [Ref.26026377]Human endocervical cells End1/E6E7:50% cell death at 12.5 µM. |
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| N-terminal Modification | Free |
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| C-terminal Modification | Amidation |
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| Linear/Cyclic/Branched | Linear |
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| Uniprot |
P56230 |
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| PDB |
|
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| 3D View | |
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| PDB Download | Download PDB Predicted by Alphafold2 |
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| PubMed ID | 26026377, 15203252, PubMed ID is not available |
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