Basic Information

IDDRAMP01557
SequenceGLFKVLGSVAKHLLPHVAPVIAEKL
Length25
NameCaerin-1.7 (Frogs, amphibians, animals)
SourceLitoria xanthomera (Orange-thighed frog) (Litoria chloris)
ActivityAntimicrobial, Antibacterial,Antiviral
Pathogen[Ref.26026377]Virus:HIV: inhibition of HIV Pseudovirus (PsV) infection in CD4+ T cells(IC50=2.5 µM).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity[Ref.26026377]Human endocervical cells End1/E6E7:50% cell death at 12.5 µM.
N-terminal ModificationFree
C-terminal ModificationAmidation
Linear/Cyclic/BranchedLinear
Uniprot P62548, P62549, P56232, P81250
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID26026377, 9230483, 9204574, 9516047

Physicochemical Properties

Residues25
SequenceGLFKVLGSVAKHLLPHVAPVIAEKL
Molecular Weight2637.212
Grand Average of Hydropathy0.884
Isoelectric Point9.703
Charge at pH 7.41.624
Secondary StructureHelix: 0.440, Turn: 0.200, Sheet: 0.360
Instability Index19.908
Aromaticity0.04

Similar Structure Search

Candidates based on structure

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